• Autoimmunity and Environment: Am I at risk? 

      Smyk, D.; Rigopoulou, E. I.; Baum, H.; Burroughs, A. K.; Vergani, D.; Bogdanos, D. P. (2012)
      The complex interplay between environmental factors and genetic susceptibility plays an essential role in disease pathogenesis. This is especially true for autoimmunity, where clinical reports, genomic and epidemiological ...
    • Familial primary biliary cirrhosis: Like mother, like daughter? 

      Smyk, D. S.; Rigopoulou, E. I.; Pares, A.; Mytilinaiou, M. G.; Invernizzi, P.; Bogdanos, D. P. (2012)
      The reasons underlying why autoimmune diseases overwhelmingly affect women more than men are not clear. Nor are the reasons why autoimmune disease is more prevalent in families. This review uses primary biliary cirrhosis ...
    • Helicobacter pylori and autoimmune disease: Cause or bystander 

      Smyk, D. S.; Koutsoumpas, A. L.; Mytilinaiou, M. G.; Rigopoulou, E. I.; Sakkas, L. I.; Bogdanos, D. P. (2014)
      Helicobacter pylori (H. pylori) is the main cause of chronic gastritis and a major risk factor for gastric cancer. This pathogen has also been considered a potential trigger of gastric autoimmunity, and in particular of ...
    • p38 mitogen-activated protein kinase (p38 MAPK)-mediated autoimmunity: Lessons to learn from ANCA vasculitis and pemphigus vulgaris 

      Mavropoulos, A.; Orfanidou, T.; Liaskos, C.; Smyk, D. S.; Billinis, C.; Blank, M.; Rigopoulou, E. I.; Bogdanos, D. P. (2013)
      Evidence is beginning to accumulate that p38 mitogen activated protein kinase (p38 MAPK) signaling pathway plays an important role in the regulation of cellular and humoral autoimmune responses. The exact mechanisms and ...
    • Peculiar antibody reactivity to human connexin 37 and its microbial mimics in patients with Crohn's disease 

      Koutsoumpas, A.; Polymeros, D.; Tsiamoulos, Z.; Smyk, D.; Karamanolis, G.; Triantafyllou, K.; Rigopoulou, E. I.; Forbes, A.; Vergani, D.; Bogdanos, D. P.; Ladas, S. D. (2011)
      Background/aims: We found that pooled Crohn's disease (CD) sera strongly react with a human gap-junction connexin 37 (Cx37) peptide and tested for anti-Cx37 antibody reactivity in sera from CD patients and controls. We ...
    • Sex Differences Associated with Primary Biliary Cirrhosis 

      Smyk, D. S.; Rigopoulou, E. I.; Pares, A.; Billinis, C.; Burroughs, A. K.; Muratori, L.; Invernizzi, P.; Bogdanos, D. P. (2012)
      Primary biliary cirrhosis (PBC) is a cholestatic liver disease of autoimmune origin, characterised by the destruction of small intrahepatic bile ducts. The disease has an unpredictable clinical course but may progress to ...